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The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.

Pharmacogenetics and genomics - 1 Jun 2009

Lea Rod, Colson Natalie, Quinlan Sharon, Macmillan John, Griffiths Lyn

Abstract excerpt

BACKGROUND: Migraine is a prevalent and debilitating disease that may, in part, arise because of disruption in neurovascular endothelia caused by elevated homocysteine. This study examined the homocysteine-lowering effects of vitamin supplementation on migraine disability, frequency and severity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 19384265
DOI: 10.1097/FPC.0b013e32832af5a3

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19384265-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The effects of vitamin supplementation and MTHFR (C677T) genotype on homocysteine-lowering and migraine disability.PMID 19384265Read ↗

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The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.Semantic proximity Read ↗

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