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Article

Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study.

BMC medical genetics - 7 Mar 2011

Uchida Yasue, Sugiura Saiko, Ando Fujiko, Nakashima Tsutomu, Shimokata Hiroshi

Abstract excerpt

BACKGROUND: Recent investigations demonstrated many genetic contributions to the development of human age-related hearing impairment (ARHI), however, reports of factors associated with a reduction in the ARHI risk are rare. Folate metabolism is essential for cellular functioning. Despite the extensive investigations regarding the roles of folate metabolism related gene polymorphisms in the pathophysiology of...

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Source

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Identifiers

PMID: 21385350
DOI: 10.1186/1471-2350-12-35
PMCID: PMC3063203

Genes

MTHFR
MTR

Variants

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