Article
Mutagenicity of the mycotoxin alternariol in cultured mammalian cells.
Toxicology letters - 14 Jul 2006
Brugger Eva-Maria, Wagner Jörg, Schumacher David M, Koch Karen, Podlech Joachim, Metzler Manfred, Lehmann Leane
Abstract excerpt
The mycotoxin alternariol (AOH) is an important contaminant of fruit and cereal products. Concern about exposure to low levels of AOH was raised after the disclosure that contamination of food with the AOH-producing species Alternaria alternata is associated with oesophagal cancer. Previously we have reported that AOH induces kinetochore-negative micronuclei in cultured Chinese hamster V79 cells. The present...
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