Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant frequency in comparison to oxidative DNA damage induced by ochratoxin A in L5178Y tk+/- (3.7.2C) mouse lymphoma cells.

Drug and chemical toxicology - 1 Apr 2014

Ali Rahat, Guo Xiaoqing, Lin Haixia, Khan Qaiser M, Ismail Muhammad, Waheed Usman, Ali Tayyaba, Bhalli Javed A

Abstract excerpt

Ochratoxin A (OTA) is a naturally occurring mycotoxin that contaminates animal feed and human food. OTA is nephrotoxic, hepatotoxic, immunosuppressive and a potent renal carcinogen in rodents. In the present study, we evaluated the genotoxicity of OTA in L5178Y tk(+/-) (3.7.2C) mouse lymphoma cells using the microwell version of the mouse lymphoma gene mutation assay (MLA) and the comet assay modified to detect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to DNA Damage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Lymphoma

Share to Mutagens

Share to Mutation

Share to Oxidation-Reduction

Source

Identifiers

PMID: 24164384
DOI: 10.3109/01480545.2013.838775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant frequency in comparison to oxidative DNA damage induced by ochratoxin A in L5178Y tk+/- (3.7.2C) mouse lymphoma cells.PMID 24164384Read ↗

Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress.Semantic proximity Read ↗

In vitro mouse lymphoma (L5178Y Tk⁺/⁻-3.7.2C) forward mutation assay.Semantic proximity Read ↗

In Vitro Mouse Lymphoma Cell (L5178Y Tk+/- 3.7.2C) Forward Mutation Assay.Semantic proximity Read ↗

Analysis of the genotoxicity of anthraquinone dyes in the mouse lymphoma assay.Semantic proximity Read ↗

The L5178Y/tk+/- mouse lymphoma specific gene and chromosomal mutation assay a phase III report of the U.S. Environmental Protection Agency Gene-Tox Program.Semantic proximity Read ↗

Detection of Loss of Heterozygosity in Tk-Deficient Mutants from L5178Y Tk+/--3.7.2C Mouse Lymphoma Cells.Semantic proximity Read ↗

Can the L5178Y Tk+/- mouse lymphoma assay detect epigenetic silencing?Semantic proximity Read ↗

The mouse lymphoma assay.Semantic proximity Read ↗

Whole genome sequencing of mouse lymphoma L5178Y-3.7.2C (TK+/-) reveals millions of mutations and genetic markers.Semantic proximity Read ↗

Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells.Semantic proximity Read ↗

Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate.Semantic proximity Read ↗

The use of L5178Y mouse lymphoma cells to assess the mutagenic, clastogenic and aneugenic properties of chemicals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.