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Article

STAT3 is activated in a subset of the Ewing sarcoma family of tumours

3 Feb 2006

Abstract excerpt

STAT3 is an oncogene that regulates critical cellular processes and whose constitutive activation has been demonstrated to correlate with biological and clinical features in many types of human malignancy. In this study, STAT3 activation was assessed in the Ewing sarcoma family of tumours (ESFT), which is characterized by fusion of the EWS gene with one of several Ets transcription factors, most commonly...

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PMID: 16463269
DOI: 10.1002/path.1941

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