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Article

Genetic variants of GRK4 influence circadian rhythm of blood pressure and response to candesartan in hypertensive patients.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 3 Oct 2021

Cao Nian, Tang Hui, Tian Miao, Gong Xue, Xu Zaicheng, Zhou Binqing, Lan Cong, Chen Caiyu, Qu Shuang, Zheng Shuo, Ren Hongmei, Fan Chao, Jose Pedro A, Zeng Chunyu, Xia Tianyang

Abstract excerpt

Background: Genetic variants of coding genes related to blood pressure regulation participate in the pathogenesis of hypertension and determines the response to specific antihypertensive drugs. G protein-coupled receptor kinase 4 (GRK4) and its variants are of great importance in pathogenesis of hypertension. However, little is known about role of GRK4 variants in determine circadian rhythm of blood pressure and...

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Identifiers

PMID: 33899625
DOI: 10.1080/10641963.2021.1919357
PMCID: PMC8565180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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