Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hematopoietic Engraftment of Human Embryonic Stem Cell‐Derived Cells Is Regulated by Recipient Innate Immunity

3 Feb 2006

Abstract excerpt

Human embryonic stem cells (hESCs) provide an important means to characterize early stages of hematopoietic development. However, the in vivo potential of hESC-derived hematopoietic cells has not been well defined. We demonstrate that hESC-derived cells are capable of long-term hematopoietic engraftment when transplanted into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. Human CD45(+) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Pluripotent Stem Cells Research
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16456127
DOI: 10.1634/stemcells.2005-0340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hematopoietic Engraftment of Human Embryonic Stem Cell‐Derived Cells Is Regulated by Recipient Innate ImmunityPMID 16456127Read ↗

Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells.Semantic proximity Read ↗

Differentiation of Human Embryonic Stem Cells After Transplantation in Immune‐Deficient MiceSemantic proximity Read ↗

Brief Report—Human Embryonic Stem Cell-Derived Mesenchymal Progenitors Possess Strong Immunosuppressive Effects Toward Natural Killer Cells as Well as T LymphocytesSemantic proximity Read ↗

Concise Review: One Stone for Multiple Birds: Generating Universally Compatible Human Embryonic Stem CellsSemantic proximity Read ↗

Human Embryonic Stem Cells and Their Differentiated Derivatives Are Less Susceptible to Immune Rejection Than Adult CellsSemantic proximity Read ↗

Insensitivity of Human iPS Cells-Derived Mesenchymal Stem Cells to Interferon-γ-induced HLA Expression Potentiates Repair Efficiency of Hind Limb Ischemia in Immune Humanized NOD Scid Gamma MiceSemantic proximity Read ↗

Nonirradiated NOD,B6.SCID Il2rγ-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells.Semantic proximity Read ↗

CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent miceSemantic proximity Read ↗

Memory T Cells in MHC-Deficient Humanized MiceSemantic proximity Read ↗

Long-term engraftment of adult hematopoietic progenitors in a novel model of humanized miceSemantic proximity Read ↗

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-toleranceSemantic proximity Read ↗

Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.