Article
The lipoprotein LpqW is essential for the mannosylation of periplasmic glycolipids in Corynebacteria.
The Journal of biological chemistry - 14 Dec 2012
Rainczuk Arek K, Yamaryo-Botte Yoshiki, Brammananth Rajini, Stinear Timothy P, Seemann Torsten, Coppel Ross L, McConville Malcolm J, Crellin Paul K
Abstract excerpt
Phosphatidylinositol mannosides (PIM), lipomannan (LM), and lipoarabinomannan (LAM) are essential components of the cell wall and plasma membrane of mycobacteria, including the human pathogen Mycobacterium tuberculosis, as well as the related Corynebacterineae. We have previously shown that the lipoprotein, LpqW, regulates PIM and LM/LAM biosynthesis in mycobacteria. Here, we provide direct evidence that LpqW...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
