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Article

Locally weighted transmission/disequilibrium test for genetic association analysis.

BMC genetics - 30 Dec 2005

Hsu Li, Yu Xuesong, Houwing-Duistermaat Jeanine J, Uh Hae-Won, El Galta Rachid, Lebrec Jeremie J P, Tang Hua

Abstract excerpt

The transmission/disequilibrium test statistic has been used for assessing genetic association in affected-parent trios. In the presence of multiple tightly linked marker loci where local dependency may exist, haplotypes are reconstructed statistically to estimate the joint effects of these markers. In this manuscript, we propose an alternative to the haplotype approach by taking a weighted average of multiple...

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PMID: 16451673
DOI: 10.1186/1471-2156-6-S1-S60
PMCID: PMC1866722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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