Article
A general class of association tests for family-based data using weight functions.
Genetic epidemiology - 1 Apr 2003
Liu Xin, Gordon Derek
Abstract excerpt
Based on the symmetry of transmitted/nontransmitted alleles from heterozygous parents under the null hypothesis of no association, the work proposed here establishes a general statistical framework for constructing association tests with data from nuclear families with multiple affected children. A class of association tests is proposed for both diallelic and multiallelic markers. The proposed test statistics...
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