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Immortalized keratinocyte lines derived from human embryonic stem cells

30 Jan 2006

Abstract excerpt

Cells of the human embryonic stem (hES) cell line H9, when cultured in the form of embryoid bodies, give rise to cells with markers of the keratinocyte of stratified squamous epithelia. Keratinocytes also form in nodules produced in scid mice by injected H9 cells; the hES-derived keratinocytes could be recovered in culture, where their colonies underwent a peculiar form of fragmentation. Whether formed from...

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PMID: 16446420
DOI: 10.1073/pnas.0510953103

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