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Article

Different immortalized keratinocyte cell lines display distinct capabilities to differentiate and reconstitute an epidermis in vitro

3 Dec 2023

Abstract excerpt

Abstract Dermatological research relies on the availability of suitable models that most accurately reflect the in vivo situation. Primary keratinocytes obtained from skin reduction surgeries are not only limited by availability but have a short lifespan and show donor‐specific variations, which hamper the understanding of general mechanisms. The spontaneously immortalized keratinocyte cell line HaCaT displays...

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PMID: 38043130
DOI: 10.1111/exd.14985

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