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Contrasting Expression of Keratins in Mouse and Human Embryonic Stem Cells

17 Oct 2008

Abstract excerpt

RNA expression data reveals that human embryonic stem (hES) cells differ from mouse ES (mES) cells in the expression of RNAs for keratin intermediate filament proteins. These differences were confirmed at the cellular and protein level and may reflect a fundamental difference in the epithelial nature of embryonic stem cells derived from mouse and human blastocysts. Mouse ES cells express very low levels of the...

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PMID: 18941637
DOI: 10.1371/journal.pone.0003451

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