Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures

Abstract excerpt

Human multipotent skin derived precursor cells (SKPs) are traditionally sourced from dissociated dermal tissues; therefore, donor availability may become limiting. Here we demonstrate that both normal and diseased adult human dermal fibroblasts (DF) pre-cultured in conventional monolayers are capable of forming SKPs (termed m-SKPs). Moreover, we show that these m-SKPs can be passaged and that cryopreservation of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hair Growth and Disorders
• Share to Skin and Cellular Biology Research
• Share to Wnt/β-catenin signaling in development and cancer