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Article

Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells.

Biochemical and biophysical research communications - 24 Oct 2003

Jones L C, Tran C T L, Leiper J M, Hingorani A D, Vallance P

Abstract excerpt

Synthesis of the vasodilator nitric oxide (NO) can be inhibited by the endogenous methylarginines L-NMMA and ADMA. ADMA is elevated in a number of cardiovascular disorders in which NO availability is reduced. Elimination of ADMA from the body occurs primarily by enzymatic breakdown through the ac...

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Source

Identifiers

PMID: 14550280
DOI: 10.1016/j.bbrc.2003.09.097

Genes

DDAH2
DDAH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14550280-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Common genetic variation in a basal promoter element alters DDAH2 expression in endothelial cells.PMID 14550280Read ↗

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