Article
Association study of dimethylarginine dimethylaminohydrolase 2 gene polymorphisms and coronary heart disease.
Molecular medicine reports - 1 Nov 2012
Xu Ai-Guo, Xu Rong-Mei, Lu Chang-Qing, Li Dan-Dan, Xu Qin-Fu, Guo Jing, Fu Xin, Zhao Wei, Yao Meng-Ying
Abstract excerpt
While a number of genetic and environmental risk factors for coronary heart disease (CHD) have been identified, the list of potential risk factors remains long. One candidate is dimethylarginine dimethylaminohydrolase (DDAH2), which is known to be polymorphic in humans. The gene product indirectly increases the endogenous production of nitric oxide, an...
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