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Article

Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim.

The Journal of biological chemistry - 7 Apr 2006

Yang Jin-Ming, O'Neill Peter, Jin Wei, Foty Ramsey, Medina Daniel J, Xu Zude, Lomas Mehnaaz, Arndt Greg M, Tang Yi, Nakada Marian, Yan Li, Hait William N

Abstract excerpt

Overexpression of extracellular matrix metalloproteinase inducer (EMMPRIN or CD147), a member of the immunoglobulin family and a glycoprotein enriched on the surface of tumor cells, promotes invasion, metastasis, and growth and survival of malignant cells and confers resistance to some chemotherapeutic drugs. However, the molecular mechanisms underlying the actions of EMMPRIN are not fully understood. In this...

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PMID: 16443928
DOI: 10.1074/jbc.M508421200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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