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Article

Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells.

Molecular cancer - 27 Jan 2015

Lim Hooi Ching, Multhaupt Hinke A B, Couchman John R

Abstract excerpt

BACKGROUND: Cell surface proteoglycans interact with numerous regulators of cell behavior through their glycosaminoglycan chains. The syndecan family of transmembrane proteoglycans are virtually ubiquitous cell surface receptors that are implicated in the progression of some tumors, including breast carcinoma. This may derive from their regulation of cell adhesion, but roles for specific syndecans are unresolved....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25623282
DOI: 10.1186/s12943-014-0279-8
PMCID: PMC4326193

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