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Article

The role of EMMPRIN in T cell biology and immunological diseases

14 May 2015

Abstract excerpt

EMMPRIN (CD147), originally described as an inducer of the expression of MMPs, has gained attention in its involvement in various immunologic diseases, such that anti-EMMPRIN antibodies are considered as potential therapeutic medications. Given that MMPs are involved in the pathogenesis of various disease states, it is relevant that targeting an upstream inducer would make for an effective therapeutic strategy....

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PMID: 25977287
DOI: 10.1189/jlb.3ru0215-045r

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