Article
EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity.
Amino acids - 1 Apr 2010
Zheng Jun-Fang, Sun Li-Cui, Liu Hua, Huang Yan, Li Yang, He Junqi
Abstract excerpt
The expression of Ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50) and the intragenic mutation of the ebp50 gene have been reported to correlate with human breast cancer development, but the exact impacts on breast cancer development and its molecular mechanism are not fully understood. In this study, we investigate the potential function of EBP50 through over-expression in the breast cancer cell line,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
