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Article

Lack of association between CTLA-4 and PDCD1 polymorphisms and acute rejection in German liver transplant recipients.

Human immunology - 1 Aug 2013

Thude Hansjörg, Schipler Anna Dorothea, Treszl Andras, Peine Sven, Koch Martina, Sterneck Martina, Nashan Björn

Abstract excerpt

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell-death 1 (PDCD1) are two genes encoding coinhibitory immunoreceptors that are involved in regulation transplant rejection and tolerance induction. Thus, CTLA-4 and PDCD1 may be good candidate genes to evaluate in liver transplant rejection. In this retrospective study, we investigated whether four functional single nucleotide polymorphisms...

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Identifiers

PMID: 23628397
DOI: 10.1016/j.humimm.2013.04.021

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PDCD1

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