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Article

Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts.

The American journal of pathology - 1 Feb 2006

Asano Yoshihide, Ihn Hironobu, Yamane Kenichi, Jinnin Masatoshi, Tamaki Kunihiko

Abstract excerpt

The biological effect of cytokines is mainly determined by the cytokine-receptor interaction, which is modulated by the concentration and the activity of cytokines and/or their receptors. Because alphav-containing integrins can bind to and/or activate latent TGF-beta, these integrins have been thought to be involved in the pathogenesis of fibrotic disorders. Our recent observations that alphavbeta5 is...

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Identifiers

PMID: 16436664
DOI: 10.2353/ajpath.2006.041306
PMCID: PMC1606497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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