Article
The α <sub>v</sub> β <sub>1</sub> integrin plays a critical in vivo role in tissue fibrosis
20 May 2015
Abstract excerpt
Integrins are transmembrane heterodimeric receptors that contribute to diverse biological functions and play critical roles in many human diseases. Studies using integrin subunit knockout mice and inhibitory antibodies have identified important roles for nearly every integrin heterodimer and led to the development of a number of potentially useful therapeutics. One notable exception is the αvβ1 integrin. αv and...
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