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Article

Association of prolactin and its receptor gene regions with familial breast cancer.

The Journal of clinical endocrinology and metabolism - 1 Apr 2006

Vaclavicek Annika, Hemminki Kari, Bartram Claus R, Wagner Kerstin, Wappenschmidt Barbara, Meindl Alfons, Schmutzler Rita K, Klaes Rüdiger, Untch Michael, Burwinkel Barbara, Försti Asta

Abstract excerpt

CONTEXT: The contribution of prolactin (PRL) through its receptor (PRLR) to the pathogenesis and progression of human mammary tumors has received recent attention. OBJECTIVE: We investigated whether genetic variation in the PRL and PRLR genes is associated with the risk of breast cancer (BC). DESIGN: We conducted a case-control study with a total of seven single nucleotide polymorphisms (SNPs). SETTING: The study...

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Source

Identifiers

PMID: 16434456
DOI: 10.1210/jc.2005-1899

Genes

PRL
PRLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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