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The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndrome

22 Nov 2023

Abstract excerpt

The prolactin receptor gene (PRLR) may contribute to polycystic ovarian syndrome (PCOS) since it plays important roles in physiological ovarian functions. PRLR-knockout mice have irregular cycles and subfertility and variants in or around the PRLR gene were associated in humans with female testosterone levels and recurrent miscarriage. We tested 40 variants in the PRLR gene in 212 Italian families phenotyped by...

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PMID: 37993904
DOI: 10.1186/s13048-023-01280-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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