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Article

Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness

15 Sept 2022

Abstract excerpt

The prolactin receptor (PRLR) is a member of the lactogen/cytokine receptor family, which mediates multiple actions of prolactin (PRL). PRL is a major hormone in the proliferation/differentiation of breast epithelium that is essential for lactation. It is also involved in breast cancer development, tumor growth and chemoresistance. Human PRLR expression is controlled at the transcriptional level by multiple...

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PMID: 36187116
DOI: 10.3389/fendo.2022.949396

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