Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Could prolactin receptor gene polymorphism play a role in pathogenesis of breast carcinoma?

Current medical research and opinion - 1 Apr 2004

Canbay Emel, Degerli Naci, Gulluoglu Bahadir M, Kaya Handan, Sen Metin, Bardakci Fevzi

Abstract excerpt

OBJECTIVE: Constitutive activation of various hormone and growth factor receptors is newly recognised as a common cause of tumour development. This study investigated the presence of any mutation or polymorphism of prolactin receptor (PRLR) in 38 patients with breast cancer. RESEARCH METHODS: Genomic DNA was extracted and PCR amplification was carried out for exon 1-10 of PRLR from tumoral and adjacent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Exons
Share to Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single-Stranded Conformational

Share to Receptors, Estrogen

Share to Receptors, Progesterone

Share to Receptors, Prolactin

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 15119991
DOI: 10.1185/030079904125003232

Genes

PRLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Could prolactin receptor gene polymorphism play a role in pathogenesis of breast carcinoma?PMID 15119991Read ↗

Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in Poland.Semantic proximity Read ↗

Association of prolactin and its receptor gene regions with familial breast cancer.Semantic proximity Read ↗

Association of gene polymorphisms in prolactin and its receptor with breast cancer risk in Taiwanese women.Semantic proximity Read ↗

Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasivenessSemantic proximity Read ↗

New concepts in prolactin biology.Semantic proximity Read ↗

Association of prolactin receptor (PRLR) variants with prolactinomasSemantic proximity Read ↗

Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment.Semantic proximity Read ↗

Prolactin and human tumourogenesis.Semantic proximity Read ↗

Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.Semantic proximity Read ↗

A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort.Semantic proximity Read ↗

The prolactin receptor gene (PRLR) is linked and associated with the risk of polycystic ovarian syndromeSemantic proximity Read ↗

Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: Promoter usage and alternative mRNA splicingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.