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Article

IL-18 gene polymorphism confers susceptibility to the development of anti-GAD65 antibody in Graves' disease.

Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 2006

Hiromatsu Y, Mukai T, Kaku H, Miyake I, Ichimura M, Fukutani T, Nakayama H, Takata K, Imamura Y, Shoji S, Yamada K, Koda Y, Bednarczuk T

Abstract excerpt

AIMS: This study aimed to investigate whether interleukin-18 (IL-18) gene polymorphisms are associated with the development of antibody against the 65-kDa isoform of recombinant human glutamic acid decarboxylase (GAD65Ab) in patients with Graves' disease. METHODS: A total of 398 unrelated Japanese patients with Graves' disease, with and without GAD65Ab, were recruited. Three single nucleotide polymorphisms in the...

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Identifiers

PMID: 16433722
DOI: 10.1111/j.1464-5491.2005.01734.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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