Article
High risk of cutaneous melanoma amongst carriers of the intercellular adhesion molecule-1 R241 allele.
Melanoma research - 1 Feb 2006
Vinceti Marco, Pellacani Giovanni, Casali Bruno, Malagoli Carlotta, Nicoli Davide, Farnetti Enrico, Bassissi Stefania, Bergomi Margherita, Seidenari Stefania
Abstract excerpt
We examined the relation between cutaneous melanoma risk and the intercellular adhesion molecule-1 (ICAM-1) gene single nucleotide polymorphisms G241R and K469E, as well as the circulating soluble form of ICAM-1 determined in plasma, in the population of Modena Province, northern Italy. Individuals carrying at least one R241 allele, versus those carrying the wild-type GG genotype, had a relative risk of melanoma...
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