Article
Intercellular adhesion molecule-1 genetic markers (+241G/A and +469A/G) in Iranian women with breast cancer.
Cancer genetics and cytogenetics - 1 May 2008
Arandi Nargess, Talei Abdolrasoul, Erfani Nasrollah, Ghaderi Abbas
Abstract excerpt
Breast cancer is the most common cancer among women, the second-most leading cause of women's death after lung cancer. ICAM-1 is a cell adhesion molecule that belongs to the Ig-superfamily, with a glycoprotein structure playing a key role in leukocyte recruitment into inflammatory sites, as well as in leukocyte activation and effector function. Proteolytic cleavage of ICAM-1 results in the formation of a soluble...
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