Article
ICAM-1 polymorphisms and development of cutaneous malignant melanoma.
International journal of immunogenetics - 1 Dec 2005
Howell W M, Rose-Zerilli M J, Theaker J M, Bateman A C
Abstract excerpt
Tumour growth in cutaneous malignant melanoma (CMM) is mediated by cell adhesion molecules, including intercellular adhesion molecule-1 (ICAM-1). ICAM-1 expression is associated with increasing Breslow thickness of vertical growth-phase tumours and, in patients with stage 1 disease, may be associated with disease free and patient survival. In this study we have investigated whether two single nucleotide...
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