Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

tRNA hopping: effects of mutant tRNAs.

Biochimica et biophysica acta - 20 Oct 2003

O'Connor Michael

Abstract excerpt

Movement of tRNA and mRNA through the ribosome is coupled. However, selection for suppression of a -1 frameshift mutation in Escherichia coli has yielded a class of mutant tRNAs that can violate this mechanism and "hop" or disengage from their cognate codons and re-pair downstream in the mRNA. Previously described tRNA mutants of this class included those with insertions in the anticodon of tRNA(Val)1. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticodon
Share to Biological Transport, Active
Share to Frameshift Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribosomes

Share to RNA, Bacterial

Share to RNA Stability

Share to RNA, Transfer

Share to Suppression, Genetic

Source

Identifiers

PMID: 14580678
DOI: 10.1016/j.bbaexp.2003.09.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

tRNA hopping: effects of mutant tRNAs.PMID 14580678Read ↗

An active role for tRNA in decoding beyond codon:anticodon pairing.Semantic proximity Read ↗

tRNA residues evolved to promote translational accuracy.Semantic proximity Read ↗

Aminoacylation of tRNA in the evolution of an aminoacyl-tRNA synthetase.Semantic proximity Read ↗

tRNA genes rapidly change in evolution to meet novel translational demands.Semantic proximity Read ↗

Tertiary structure base pairs between D- and TpsiC-loops of Escherichia coli tRNA(Leu) play important roles in both aminoacylation and editing.Semantic proximity Read ↗

Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases.Semantic proximity Read ↗

Importance of the reverse Hoogsteen base pair 54-58 for tRNA function.Semantic proximity Read ↗

A new model for phenotypic suppression of frameshift mutations by mutant tRNAs.Semantic proximity Read ↗

Idiosyncratic tuning of tRNAs to achieve uniform ribosome binding.Semantic proximity Read ↗

How mutations in tRNA distant from the anticodon affect the fidelity of decoding.Semantic proximity Read ↗

Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis.Semantic proximity Read ↗

Disrupted tRNA gene diversity and possible evolutionary scenarios.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.