Article
Characterization of the adr1-1 nonsense mutation identifies the translational start of the yeast transcriptional activator ADR1.
Yeast (Chichester, England) - 1 Jan 2000
Bemis L T, Denis C L
Abstract excerpt
We have characterized a nonsense mutation in the ADR1 gene that identifies the translational start of the ADR1 protein. The ADR1 gene of Saccharomyces cerevisiae is required for synthesis of the glucose-repressible alcohol dehydrogenase (ADH2). The adr1-1 mutation, which inhibits ADH2 expression, was identified as a C to G transversion at base pair +32. This alteration would result in a UGA nonsense codon in...
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