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Article

Trypanosoma cruzi modulates the profile of memory CD8+ T cells in chronic Chagas' disease patients

23 Jan 2006

Abstract excerpt

We present a cross-sectional analysis of the maturation and migratory properties of the memory CD8(+) T cell compartment, in relation to the severity of heart disease in individuals with chronic Trypanosoma cruzi infection removed from endemic areas for longer than 20 years. Subjects with none or mild heart involvement were more likely to mount T. cruzi-specific memory IFN-gamma responses than subjects with more...

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PMID: 16431876
DOI: 10.1093/intimm/dxh387

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