Article
Differential phenotypic and functional profile of epitope-specific cytotoxic CD8+ T cells in benznidazole-treated chronic asymptomatic Chagas disease patients.
Biochimica et biophysica acta. Molecular basis of disease - 1 Mar 2020
Egui Adriana, López Manuel Carlos, Gómez Inmaculada, Simón Marina, Segovia Manuel, Thomas M Carmen
Abstract excerpt
One of the greatest challenges in Chagas disease research is the search for tools that will enable the assessment of pharmacological treatment efficacy. A recently described set of serological biomarkers composed of four parasite antigens and established criteria of treatment efficacy allowed the evaluation of the impact of benznidazole treatment a short/medium time after the treatment. In addition, cellular...
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