Article
Phenotypic and functional characteristics of CD28+ and CD28- cells from chagasic patients: distinct repertoire and cytokine expression.
Clinical and experimental immunology - 1 Jul 2004
Menezes C A S, Rocha M O C, Souza P E A, Chaves A C L, Gollob K J, Dutra W O
Abstract excerpt
Chronic human Chagas' disease ranges from an asymptomatic to a severe cardiac clinical form. The involvement of the host's immune response in the development and maintenance of chagasic pathology has been demonstrated by several groups. We have shown that activated T-cells lacking CD28 expression are increased in the peripheral blood of chagasic patients (CP), suggesting a relationship between these cells and...
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