Article

Immunologic changes are detectable in the peripheral blood transcriptome of clinically asymptomatic Chagas cardiomyopathy patients

2023-10-05

Abstract excerpt

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi , is a neglected parasitic disease that affects approximately 6 million individuals worldwide. Of those infected, 20-30% will go on to develop chronic Chagas cardiomyopathy (CCC), and ultimately many of these individuals will progress to advanced heart failure. The mechanism by which this progression occurs is poorly understood, as few studies hav...

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Literature Corpus work: 2cdf8e26-854a-596e-a954-5779873431dd
DOI: 10.1101/2023.10.03.560680

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