Article
The tumour necrosis factor (TNF)-alpha-308GA promoter polymorphism is related to prenatal growth and postnatal insulin resistance.
Clinical endocrinology - 1 Feb 2006
Casano-Sancho Paula, López-Bermejo Abel, Fernández-Real José Manuel, Monrós Eugènia, Valls Carme, Rodríguez-González Francesc-Xavier, Ricart Wifredo, Ibáñez Lourdes
Abstract excerpt
OBJECTIVE: Variation in the tumour necrosis factor gene, (TNF) has been associated with insulin resistance traits. We questioned whether the TNF-308G/A polymorphism is associated with birthweight and insulin resistance in children born small for gestational age (SGA), a patient population known to be at risk for insulin resistance. DESIGN: A cross-sectional, hospital-based study assessing insulin sensitivity in...
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