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Article

The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome.

American journal of hypertension - 1 Oct 2005

Sookoian Silvia, García Silvia I, Gianotti Tomás Fernández, Dieuzeide Guillermo, González Claudio D, Pirola Carlos J

Abstract excerpt

BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) has been associated with obesity, obesity-related hypertension, and metabolic syndrome. We investigated the possible contribution of the G-308A TNF-alpha mutant to explain variables of the metabolic syndrome. METHODS: Data and blood samples were used from the 175 adolescents that satisfied the criterion of having systolic or diastolic blood pressures (BP) more...

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Source

Identifiers

PMID: 16202847
DOI: 10.1016/j.amjhyper.2005.04.014

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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