Article
Insulin family polymorphisms in pregnancies complicated by small for gestational age infants.
Molecular human reproduction - 1 Sept 2015
Andraweera Prabha H, Gatford Kathryn L, Dekker Gustaaf A, Leemaqz Shalem, Russell Darryl, Thompson Steven D, McCowan Lesley, Roberts Claire T
Abstract excerpt
Being born small for gestational age (SGA) increases the risk for adverse perinatal outcomes and later life vascular and metabolic disorders. The insulin family plays a vital role in intrauterine growth. We investigated the association of functional SNPs in insulin (INS), insulin receptor (INSR) and insulin receptor substrate 2 (IRS2) with small for gestational age (SGA) pregnancies, uterine and umbilical artery...
Topics
- Adult
- Antigens, CD
- Birth Weight
- Case-Control Studies
- Chi-Square Distribution
- Female
- Gene Frequency
- Genetic Association Studies
- Gestational Age
- Heterozygote
- Homozygote