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Article

Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2006

Yuan Bibo, Xu Yi, Woo Ju-Hyung, Wang Yunyue, Bae Young Kyung, Yoon Dae-Sung, Wersto Robert P, Tully Ellen, Wilsbach Kathleen, Gabrielson Edward

Abstract excerpt

PURPOSE: Most breast cancers have chromosomal instability that seems related to defective mitotic spindle checkpoints. Because the molecular basis of this defect is unknown, we evaluated breast cancer cell lines and tissues for possible defects involving the major mitotic checkpoint genes responsible for maintaining chromosomal stability. EXPERIMENTAL DESIGN: We analyzed sequences and expression levels (RNA and...

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Share to Adenocarcinoma, Mucinous
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16428479
DOI: 10.1158/1078-0432.CCR-05-0903

Genes

BUB1
BUB3
CDC20
TTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.PMID 16428479Read ↗

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