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Article

Genetic variation in the major mitotic checkpoint genes and risk of breast cancer: a multigenic study on cancer susceptibility.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014

Wang Ping, Wang Yong, Yan Haichao, Xie Qiuping, Zhao Liang, Xu Shaoming, Zhao Qunzi

Abstract excerpt

The mitotic checkpoint system is a mechanism essential for maintaining genomic stability and defects which have been linked to cancer development. We conducted this hospital-based case-control study to investigate whether genetic variants in three major spindle checkpoint genes (BUB3, MAD2L1, and BUB1) had any bearing on an individual risk of breast cancer (BC). A total of 462 incident BC patients and 529...

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Source

Identifiers

PMID: 24711138
DOI: 10.1007/s13277-014-1906-0

Genes

BUB1
BUB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the major mitotic checkpoint genes and risk of breast cancer: a multigenic study on cancer susceptibility.PMID 24711138Read ↗

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