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Integration of hepatitis B virus DNA into chromosomal DNA during acute hepatitis B

1 Jan 2005

Abstract excerpt

AIM: To examine the serum from black African patients with acute hepatitis B to ascertain if integrants of viral DNA can be detected in fragments of cellular DNA leaking from damaged hepatocytes into the circulation. METHODS: DNA was extracted from the sera of five patients with uncomplicated acute hepatitis B and one with fulminant disease. Two subgenomic PCRs designed to amplify the complete genome of HBV were...

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Identifiers

PMID: 16425409
DOI: 10.3748/wjg.v11.i41.6416

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