Article
Meta-analysis of association of rare mutations and common sequence variants in the MSR1 gene and prostate cancer risk.
The Prostate - 15 May 2006
Sun Jielin, Hsu Fang-Chi, Turner Aubrey R, Zheng S Lilly, Chang Bao-Li, Liu Wennuan, Isaacs William B, Xu Jianfeng
Abstract excerpt
BACKGROUND: MSR1 has been reported to be associated with increased risk of prostate cancer (PCa). METHODS: We performed a meta-analysis of all eight published studies to evaluate the pooled effect of three rare mutations (R293X, S41T, and D174Y) and five common sequence variants (PRO3, INDEL1, IVS5-59, P275A, and INDEL7), stratified by race and sporadic/hereditary cancer. RESULTS: Several variants were...
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