Article
Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2005
Hope Questa, Bullock Sarah, Evans Christopher, Meitz Julia, Hamel Nancy, Edwards Stephen M, Severi Gianluca, Dearnaley David, Jhavar Sameer, Southgate Christine, Falconer Alison, Dowe Anna, Muir Kenneth, Houlston Richard S, Engert James C, Roquis David, Sinnett Daniel, Simard Jacques, Heimdal Ketil, Møller Pål, Maehle Lovise, Badzioch Michael, Eeles Rosalind A, Easton Douglas F, English Dallas R, Southey Melissa C, Hopper John L, Foulkes William D, Giles Graham G
Abstract excerpt
BACKGROUND: Variants in the gene encoding the macrophage scavenger receptor 1 (MSR1(4)) protein have been identified in men with prostate cancer, and several small studies have suggested that the 999C>T (R293X) protein-truncating mutation may be associated with an increased risk for this disease. METHODS: Using large case-control, cohort, and prostate cancer family studies conducted in several Western countries,...
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