Article
MSR1 variants and the risks of prostate cancer and benign prostatic hyperplasia: a population-based study in China.
Carcinogenesis - 1 Dec 2007
Hsing Ann W, Sakoda Lori C, Chen Jinbo, Chokkalingam Anand P, Sesterhenn Isabel, Gao Yu-Tang, Xu Jianfeng, Zheng S Lilly
Abstract excerpt
Data from epidemiologic and twin studies suggest an important role of genetic susceptibility in prostate cancer. Variants of the macrophage scavenger receptor 1 (MSR1) gene have been linked to both hereditary and sporadic prostate cancer, although the evidence is inconclusive. Most studies have been conducted on Caucasians. The role of MSR1 in prostate cancer development among Asians, for whom rates of prostate...
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