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Article

Oct-4 expression in human endometrium

1 Jan 2006

Abstract excerpt

The transcription factor Oct-4 is crucial for the maintenance of cell pluripotency and is known to be expressed in embryonic stem cells, germ cells and whole embryos at various stages of development. Oct-4 regulates cell fate in a dose-dependent manner and plays a key role in germ-cell tumours. In the past, several stem-cell markers have been detected, and their role in the pathogenesis of diseases has been...

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PMID: 16421218
DOI: 10.1093/molehr/gah254

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