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Article

OCT4 expression in human uterine myometrial stem/progenitor cells

24 Jun 2010

Abstract excerpt

BACKGROUND: The transcription factor, octamer-binding transcription factor 4 (OCT4)/POU5F1, is expressed in embryonic stem cells, germ cells and some types of adult stem cells. Human OCT4 encodes two isoforms, OCT4A and OCT4B. While OCT4A plays a crucial role in the maintenance of stem cell properties, including pluripotency, whereas OCT4B does not. We previously reported that human myometrium contains side...

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Share to Gynecological conditions and treatments
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PMID: 20576635
DOI: 10.1093/humrep/deq163

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