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Article

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jan 2006

Liu Ying, Bodmer Walter F

Abstract excerpt

A comprehensive analysis of the TP53 gene and its protein status was carried out on a panel of 56 colorectal cancer cell lines. This analysis was based on a combination of denaturing HPLC mutation screening of all exons of the p53 gene, sequencing the cDNA, and assessing the function of the p53 protein by assaying the induced expression of phosphorylated p53 and p21 after exposing cells to gamma-rays. In a few...

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Identifiers

PMID: 16418264
DOI: 10.1073/pnas.0510146103
PMCID: PMC1327731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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