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Article

Suppressor analysis of a histone defect identifies a new function for the hda1 complex in chromosome segregation.

Genetics - 1 May 2006

Kanta Hasna, Laprade Lisa, Almutairi Abeer, Pinto Inés

Abstract excerpt

Histones are essential for the compaction of DNA into chromatin and therefore participate in all chromosomal functions. Specific mutations in HTA1, one of the two Saccharomyces cerevisiae genes encoding histone H2A, have been previously shown to cause chromosome segregation defects, including an increase in ploidy associated with altered pericentromeric chromatin structure, suggesting a role for histone H2A in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16415367
DOI: 10.1534/genetics.105.050559
PMCID: PMC1461434

Genes

MKS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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